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Azithromycin is indicated for infections caused by susceptible pathogens in lower respiratory tract infections, including bronchitis and pneumonia, odontostomatologic infections, skin and soft tissue infections, acute otitis media, and upper respiratory tract infections, including sinusitis and Pharyngitis / tonsillitis. (Penicillin is generally the drug of choice in the treatment of pharyngitis caused by Streptococcus pyogenes, including the prophylaxis of rheumatic fever. Azithromycin, in general, is effective in eradicating oropharyngeal streptococcus; however, There are no data establishing the efficacy of azithromycin and subsequent prevention of rheumatic fever). In sexually transmitted diseases in men and women, azithromycin is indicated for the treatment of uncomplicated genital infections caused by Chlamydia trachomatis. It is also indicated in the treatment of chancroid caused by Haemophilus ducreyi and uncomplicated genital infection caused by non-multiresistant Neisseria gonorrhoeae; Concurrent infection with Treponema pallidum should be excluded. Azithromycin is indicated, either alone or in combination with rifabutin, for the prophylaxis of infection caused by the Mycobacterium avium-intracellulare (MAC) complex; An opportunistic infection prevalent in patients infected with the human immunodeficiency virus (HIV) at an advanced stage.